Large language models (LLMs) have been shown to be able to perform new tasks based on a few demonstrations or natural language instructions. While these capabilities have led to widespread adoption, most LLMs are developed by resource-rich organizations and are frequently kept from the public. As a step towards democratizing this powerful technology, we present BLOOM, a 176B-parameter open-access language model designed and built thanks to a collaboration of hundreds of researchers. BLOOM is a decoder-only Transformer language model that was trained on the ROOTS corpus, a dataset comprising hundreds of sources in 46 natural and 13 programming languages (59 in total). We find that BLOOM achieves competitive performance on a wide variety of benchmarks, with stronger results after undergoing multitask prompted finetuning. To facilitate future research and applications using LLMs, we publicly release our models and code under the Responsible AI License.

Artificial Intelligence (AI) is having a tremendous impact across most areas of science. Applications of AI in healthcare have the potential to improve our ability to detect, diagnose, prognose, and intervene on human disease. For AI models to be used clinically, they need to be made safe, reproducible and robust, and the underlying software framework must be aware of the particularities (e.g. geometry, physiology, physics) of medical data being processed. This work introduces MONAI, a freely available, community-supported, and consortium-led PyTorch-based framework for deep learning in healthcare. MONAI extends PyTorch to support medical data, with a particular focus on imaging, and provide purpose-specific AI model architectures, transformations and utilities that streamline the development and deployment of medical AI models. MONAI follows best practices for software-development, providing an easy-to-use, robust, well-documented, and well-tested software framework. MONAI preserves the simple, additive, and compositional approach of its underlying PyTorch libraries. MONAI is being used by and receiving contributions from research, clinical and industrial teams from around the world, who are pursuing applications spanning nearly every aspect of healthcare.

语言模型既展示了定量的改进，又展示了新的定性功能，随着规模的增加。尽管它们具有潜在的变革性影响，但这些新能力的特征却很差。为了为未来的研究提供信息，为破坏性的新模型能力做准备，并改善社会有害的效果，至关重要的是，我们必须了解目前和近乎未来的能力和语言模型的局限性。为了应对这一挑战，我们介绍了超越模仿游戏基准（Big Bench）。 Big Bench目前由204个任务组成，由132家机构的442位作者贡献。任务主题是多样的，从语言学，儿童发展，数学，常识性推理，生物学，物理学，社会偏见，软件开发等等。 Big-Bench专注于被认为超出当前语言模型的功能的任务。我们评估了OpenAI的GPT型号，Google内部密集变压器体系结构和大型基础上的开关稀疏变压器的行为，跨越了数百万到数十亿个参数。此外，一个人类专家评估者团队执行了所有任务，以提供强大的基准。研究结果包括：模型性能和校准都随规模改善，但绝对的术语（以及与评估者的性能相比）；在模型类中的性能非常相似，尽管带有稀疏性。逐渐和预测的任务通常涉及大量知识或记忆成分，而在临界规模上表现出“突破性”行为的任务通常涉及多个步骤或组成部分或脆性指标；社交偏见通常会随着含糊不清的环境而随着规模而增加，但这可以通过提示来改善。

为了与机器人合作，我们必须能够理解他们的决策。人类自然会通过类似于逆增强学习（IRL）的方式来推理其可观察到的行为，从而推断出其他代理商的信念和欲望。因此，机器人可以通过提供对人类学习者的IRL提供信息的示威来传达他们的信念和欲望。一项内容丰富的演示是，鉴于他们当前对机器人决策的理解，与学习者对机器人将要做的事情的期望有很大差异。但是，标准IRL并未对学习者的现有期望进行建模，因此不能执行这种反事实推理。我们建议将学习者对机器人决策的当前理解纳入我们的人类IRL模型中，以便机器人可以选择最大化人类理解的演示。我们还提出了一种新颖的措施，以估计人类在看不见环境中预测机器人行为的实例的难度。一项用户研究发现，我们的测试难度与人类绩效和信心息息相关。有趣的是，选择人类的信念和反事实时，选择示范会在易于测试中降低人类绩效，但在困难测试中提高了性能，从而提供了有关如何最好地利用此类模型的见解。

人工智能/机器学习方法的进步提供了在科学研究中具有广泛适用性的工具。这些技术正在跨越核物理研究主题的多样性，从而推进将有助于科学发现和社会应用。该审查提供了一种由人工智能和机器学习技术改变的核物理研究的快照。

本文探讨了超线性增长趋势的环境影响，从整体角度来看，跨越数据，算法和系统硬件。我们通过在行业规模机器学习用例中检查模型开发周期来表征AI计算的碳足迹，同时考虑系统硬件的生命周期。进一步迈出一步，我们捕获AI计算的操作和制造碳足迹，并为硬件 - 软件设计和尺度优化的结束分析以及如何帮助降低AI的整体碳足迹。根据行业经验和经验教训，我们分享关键挑战，并在AI的许多方面上绘制了重要的发展方向。我们希望本文提出的关键信息和见解能够激发社区以环保的方式推进AI领域。

AI正在经历范式转变，随着模型的兴起（例如Bert，Dall-E，GPT-3），这些模型经过大规模的数据训练，并且可以适应广泛的下游任务。我们称这些模型基础模型来强调其至关重要但不完整的特征。该报告提供了基础模型的机会和风险的详尽说明，包括其功能（例如语言，愿景，机器人技术，推理，人类互动）和技术原则（例如，模型架构，培训程序，数据，系统，安全，安全性，评估，理论）对其应用（例如法律，医疗保健，教育）和社会影响（例如不平等，滥用，经济和环境影响，法律和道德考虑）。尽管基础模型基于标准的深度学习和转移学习，但它们的规模导致了新的新兴能力，以及它们在许多任务中的有效性都激发了同质化。同质化提供了强大的杠杆作用，但要求谨慎，因为基础模型的缺陷均由下游的所有适应模型继承。尽管即将广泛地部署基础模型，但我们目前对它们的工作方式，失败以及由于其新兴属性的影响而缺乏清晰的了解。为了解决这些问题，我们认为基础模型的许多批判性研究都需要与他们的基本社会技术性质相称。

Distribution shifts-where the training distribution differs from the test distribution-can substantially degrade the accuracy of machine learning (ML) systems deployed in the wild. Despite their ubiquity in the real-world deployments, these distribution shifts are under-represented in the datasets widely used in the ML community today. To address this gap, we present Wilds, a curated benchmark of 10 datasets reflecting a diverse range of distribution shifts that naturally arise in real-world applications, such as shifts across hospitals for tumor identification; across camera traps for wildlife monitoring; and across time and location in satellite imaging and poverty mapping. On each dataset, we show that standard training yields substantially lower out-of-distribution than in-distribution performance. This gap remains even with models trained by existing methods for tackling distribution shifts, underscoring the need for new methods for training models that are more robust to the types of distribution shifts that arise in practice. To facilitate method development, we provide an open-source package that automates dataset loading, contains default model architectures and hyperparameters, and standardizes evaluations. Code and leaderboards are available at https://wilds.stanford.edu.

Recent advances in upper limb prostheses have led to significant improvements in the number of movements provided by the robotic limb. However, the method for controlling multiple degrees of freedom via user-generated signals remains challenging. To address this issue, various machine learning controllers have been developed to better predict movement intent. As these controllers become more intelligent and take on more autonomy in the system, the traditional approach of representing the human-machine interface as a human controlling a tool becomes limiting. One possible approach to improve the understanding of these interfaces is to model them as collaborative, multi-agent systems through the lens of joint action. The field of joint action has been commonly applied to two human partners who are trying to work jointly together to achieve a task, such as singing or moving a table together, by effecting coordinated change in their shared environment. In this work, we compare different prosthesis controllers (proportional electromyography with sequential switching, pattern recognition, and adaptive switching) in terms of how they present the hallmarks of joint action. The results of the comparison lead to a new perspective for understanding how existing myoelectric systems relate to each other, along with recommendations for how to improve these systems by increasing the collaborative communication between each partner.

We consider the problem of finding an accurate representation of neuron shapes, extracting sub-cellular features, and classifying neurons based on neuron shapes. In neuroscience research, the skeleton representation is often used as a compact and abstract representation of neuron shapes. However, existing methods are limited to getting and analyzing "curve" skeletons which can only be applied for tubular shapes. This paper presents a 3D neuron morphology analysis method for more general and complex neuron shapes. First, we introduce the concept of skeleton mesh to represent general neuron shapes and propose a novel method for computing mesh representations from 3D surface point clouds. A skeleton graph is then obtained from skeleton mesh and is used to extract sub-cellular features. Finally, an unsupervised learning method is used to embed the skeleton graph for neuron classification. Extensive experiment results are provided and demonstrate the robustness of our method to analyze neuron morphology.